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IPS35 Dinov I.D. et al.





















             Figure 4: DataSifter obfuscation – trade-offs between privacy protection and
                                     preservation of data utility.

                In addition, we use established model-based and model-free techniques
            to interrogate the data (Dinov 2016, Dinov 2016, Dinov 2018, Gao, Sun et al.
            2018, Kalinin, Allyn-Feuer et al. 2018, Marino, Xu et al. 2018, Tang, Gao et al.
            2018, Zhao, Matloff et al. 2018). These include both confirmatory (hypothesis
            driven)  and  exploratory  (visual  analytics)  inferential  techniques  to  extract
            knowledge,  identify  patterns,  forecast  trends,  and  forecast  univariate
            outcomes of interest and derived computed phenotypes.

            3. Results
                Open-science  relies  heavily  on  data  sharing,  findability,  accessibility,
            interoperability,  and  reusability  (FAIR)  (Wilkinson,  Dumontier  et  al.  2016),
            open-source development (Feller and Fitzgerald 2002), and transdisciplinary
            cooperation (Kreps and Maibach 2008, Dinov 2018). Figure 5 presents some
            examples of recent results illustrating the power of advanced mathematical
            modelling techniques, statistical inferential methods, and machine learning
            strategies to analyse complex, multisource, heterogeneous, and incomplete
            datasets.


















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