Page 114 - Invited Paper Session (IPS) - Volume 2

IPS186 Fagbamigbe, A. F.
Table 2: Adjusted factors influencing the sensitivity, specificity and diagnostic
accuracy of the RDT compared with the microscopy in Nigeria 2015 MIS
Characteristics Sensitivity Specificity Diagnostic Accuracy
aOR (95% CI) p-value aOR (95% CI) p-value aOR (95% CI) p-value
Child Age (24-
59 Months)
0-6 Months 0.53 (0.04-6.84) 0.63 11.3 (2.58-49.6) 0.00 3.88 (1.16-12.9) 0.03
7-23 Months 0.52 (0.30-0.90) 0.02 2.15 (1.67-2.77) 0.00 1.32 (1.07-1.62) 0.01
Anaemia Level
(Moderate)
Severe 5.46 (1.27-23.4) 0.02 0.61 (0.3-1.24) 0.17 1.84 (1.16-2.94) 0.01
Mild 0.80 (0.41-1.56) 0.52 1.80 (1.36-2.40) 0.00 1.13 (0.89-1.44) 0.31
Not Anaemic 0.38 (0.19-0.76) 0.01 2.88 (2.15-3.86) 0.00 1.45 (1.13-1.86) 0.00
Treat Malaria
Wltw
No 1.73 (1.26-2.38) 0.00 1.53 (0.76-3.08) 0.23 1.33 (0.9-1.98) 0.16
Zone (North
West)
North Central 6.49 (1.84-22.8) 0.00 0.8 (0.55-1.17) 0.25 0.95 (0.69-1.30) 0.74
North East 1.31 (0.69-2.52) 0.41 1.15 (0.83-1.59) 0.39 1.02 (0.78-1.32) 0.89
South East 2.52 (0.6-10.55) 0.21 0.87 (0.53-1.41) 0.57 1.0 0(0.66-1.52) 1.00
South South 1.45 (0.53-3.95) 0.47 1.3 (0.79-2.13) 0.30 1.21 (0.80-1.83) 0.36
South West 3.29 (0.82-13.25) 0.09 0.78 (0.44-1.35) 0.37 0.87 (0.54-1.40) 0.58
Location

Urban 0.54 (0.23-1.27) 0.16 1.24 (0.90-1.70) 0.19 0.99 (0.74-1.31) 0.92
Female 1.40 (0.86-2.30) 0.18 1.01 (0.81-1.28) 0.91 1.06 (0.87-1.28) 0.58
Wealth Quintile
(Poorest)
Poorer 0.73 (0.38-1.40) 0.34 1.22 (0.85-1.74) 0.28 1.21 (0.91-1.59) 0.19
Middle 1.24 (0.42-3.68) 0.70 1.65 (1.08-2.53) 0.02 1.42 (1.01-2.03) 0.04
Richer 0.34 (0.10-1.13) 0.08 2.31 (1.37-3.91) 0.00 1.49 (0.95-2.32) 0.08
Richest 0.53 (0.10-2.73) 0.44 3.04 (1.61-5.71) 0.00 2.19 (1.26-3.83) 0.01

4. Discussion
This study was designed to evaluate the discriminatory and predictive
accuracy of the RDT malaria test against the microscopy smear test as the
“gold” standard. There were significant relationship and agreement between
the outcomes of the RDT and microscopy malaria test procedures. However,
the Kappa statistics at 0.55 and the Gini and Pietra indexes both at 0.6337
showed that the agreement was only good but not excellent. Generally, the
RDT was found to be more sensitive (88%) than being specific (76%). The

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