Page 132 - Special Topic Session (STS) - Volume 2
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STS466 Md. Khadzir S.A. et al.
                  more result compare to Raw data due to SNOMED CT relationship structure,
                  thus capturing all the subtypes of IHD and its synonyms or ways of writing.
                     The  registry,  however,  only  captures  three  (3)  diagnosis  due  to  its
                  structured  format,  which  are  ST  Elevation  Myocardial  Infarction,  Non-ST
                  Elevation Myocardial Infarction, and Unstable Angina. This trend and pattern
                  comparison allow validation by the Clinicians and gains their buy-in in using
                  MyHarmony.
                     The  team  also  tried  to  generate  more  queries  required  by  the  NCVD
                  registry.  However,  it  was  limited  by  the  documentation  in  the  discharge
                  summary. Registry queries requires more detail information that may often
                  not documented in a discharge summary, such as information on smoking
                  status and complications of procedures.
                     After  that,  the  team  was  tasked  to  generate  National  Cardiology  Key
                  Performance Indicators (KPIs). MyHarmony are able to generate 7 out of the 8
                  KPIs (KPI 2 to 8). The first KPI was excluded because the data are available at
                  the clinic and not documented in inpatient discharge summaries. The Health
                  Information Framework (HIF) was developed for the 7 KPIs, which detailed out
                  the inclusion and exclusion criteria, the target, the formula, the terms used by
                  MyHarmony, and query, and lastly a section for additional notes.
                     Preliminary  manual  validation  on  the  completeness  and  accuracy  of
                  codified  data  shows  90%  precision  and  70%  recall.  The  content  of  those
                  records is complex as it does not follow grammar rules, and contains a large
                  number of short forms, abbreviations, acronyms and analogous terms (e.g.,
                  synd, ACS, CCS IV, NYHA 2). One example of record is “2VD with RCA culprit
                  lesion - Ad hoc PCI DES to RCA and LAD” which is challenging to codify using
                  approaches based on strict grammar. The revised version of MyHarmony uses
                  a  different  approach  based  on  shallow  parsing  and  the  consideration  of
                  multiple suitable combinations of words in a sentence. With further iterations
                  and improvement in the mapping, these challenges were overcome[3].
                     From the SNOMED CT codified database, the system was able to show a
                  more accurate result during analysis . This is because MyHarmony capitalises
                  on the existing SNOMED CT relationships structure between concepts. In this
                  case,  when  querying  “Number  of  Ischaemic  Heart  Disease  cases  per  year”,
                  MyHarmony  search  the  code  and  term  for  “Ischaemic  heart  disease”,  its
                  synonyms and accepted abbreviations, and all the subtypes of Ischaemic heart
                  disease  such  as  all  subtypes  of  “Myocardial  infarction”  and  “Angina”.
                  MyHarmony aggregates these records resulting in a more accurate analysis.
                     Usually,  the result where MyHarmony utilise SNOMED CT’s relationship
                  structure would show more records. This is because Mi-Harmony was able to
                  aggregate  data  not  just  through  String  match,  but  also  utilize  the  IS-A
                  hierarchy  structure  in  SNOMED  CT.  For  example,  querying  “Ischemic  heart
                  disease” will gather clinical records with synonymous terms like “Ischaemic

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