Page 63 - Contributed Paper Session (CPS) - Volume 3
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CPS1944 Oyelola A.
            into segments of extreme and moderate cold/heat as well as extreme and
            moderate  low/high  rainfall.  The  risks  associated  with  temperature  (with
                                                        o
            reference to optimum temperature of 28.8  C) were significantly higher for
                                         o
            temperatures lower than 25  C. For example, the cumulative associated risk
                                                              o
            over the range 0-15 lags weeks at extreme cold (16  C) and moderate cold (20
            o C) were 1.83 (95% eCI: 0.88 – 3.78) and 2.28 (95% eCI: 1.94 – 2.68, respectively
            (Table 3). The risk were higher for shorter lags and decreases over longer. In
            the case of rainfall, the cumulative effect over lag range 0  – 15 lag weeks
            revealed higher risk at moderate low rainfall (40 mm) with RR=5.49 (95% eCI:
            2.27 – 13.24).
                Using  backward  perspective  and  the  optimum  value  as  references,  the
            estimated proportions of incidence of pneumonia attributable to temperature
            and rainfall are presented in Table 4. The total attributable fraction due to
            temperature is 28.4% (95% eCI: 19.7 – 36.2). Taken separately, the total fraction
            of cases attributed to varying temperature is predominantly due to moderate
            temperatures (27.0%, 95% eCI: 17.8 – 34.8) against extreme heat (0.07%, 95%
            eCI: -0.4 – 0.6) (Table 4). The overall proportion of cases attributable to rainfall
            is  higher  than  attributable  to  temperature  however,  not  significant  (28.4%,
            95% eCI: 19.7 – 36.2 vs. 50.8%, 95% eCI: -6.4 – 76.5). Most pneumonia cases
            attributable to rainfall occurred during moderate rainfall (18.4%, 95% eCI: 8.5
            – 26.4).
                Differences were observed in the associated risk of pneumonia and varying
            temperatures and rainfall among different groups. For  example, looking at
            specific estimated risk associated with 15 weeks cumulative exposure of 20 C
                                                                                     o
            temperature, we observed; increased relative risk  of pneumonia  in females
            (RR=2.90, 95% CI: 2.31 – 3.64) compared to males (RR=1.87, 95% CI: 1.52 –
            2.30), among indigenous (RR=2.55, 95% CI: 1.82 – 3.57) vs. non-indigenous
            (RR=2.22, 95% CI: 1.86 – 2.65); emergency admission (RR=2.44, 95% CI:  2.01
            – 2.95) vs. others (RR=1.96, 95% CI: 1.45 – 2.66) and older patients aged >14
            years (RR=2.29, 95% CI: 1.43 – 3.65) against  RR=2.62 (95% CI:1.99 – 3.43) for
            14 years and less. Similarly, the pneumonia-rainfall associated risk of exposure
            to a total weekly rainfall of 40 mm (at the end of 15 weeks) is higher for females
            (RR=6.27, 95% CI: 1.87 – 21.12)  than males (RR=4.84, 95% CI: 1.54 – 15.07),
            higher among indigenous (RR=6.75, 95% CI: 1.08 – 42.36) vs. non-indigenous
            (RR=4.81, 95% CI: 1.99 – 13.64); lower for emergency admission (RR=4.82, 95%
            CI: 1.71 – 13.54) vs. others (RR=7.41, 95% CI:  1.36 – 40.28 and lower for older
            patients aged >14 years (RR=5.89, 95% CI: 1.40 – 24.78)  against RR=11.36
            (95% CI: 0.67 – 190.73) for 14 years and less.

            4.  Discussion and Conclusion
                The 2015 global burden of disease revealed that lower respiratory tract
            infections  is  the  fifth  leading  cause  of  death  worldwide[21].  Among  these,

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