Page 38 - Contributed Paper Session (CPS) - Volume 6

CPS1483 Ken Karipidis et. al
calls for all users.(17) Based on these findings it is likely that the proportion
of heavy users in our study is overestimated.
Finally this is an ecological observational study, not based on individual
data thus it is not possible to account for confounding factors. This study
design is appropriate to define global trends. Further, the stable trend in brain
tumour incidence could have concealed a true increasing risk related to mobile
phone use which appeared flat due to declines in other risk factors.
In conclusion, we found no evidence that mobile phone use increased any
brain tumour histological types or subtypes. There was an increase in the
incidence of glioblastoma prior to the rapid increase in mobile phone use
which was most likely due to improved diagnosis from MRI. Furthermore, there
was no increase in gliomas of the temporal lobe, which is the most exposed
location, during the period of substantial mobile phone use. The increase in
gliomas of the temporal lobe and decrease in gliomas of unspecified location
during the periods prior to substantial mobile phone use are in line with the
theory of improved diagnosis from CT and MRI. Further, the predicted rates
were higher than the observed rates for latency periods up to 15 years. These
results do not support an association between mobile phone use and brain
tumour, although the possibility of a small risk or a latency period of more
than 15 years cannot be excluded. Future research should continue to
investigate trends in brain tumour histological types, and anatomical location
for a possible increase with a longer latency period.

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