Page 95 - Contributed Paper Session (CPS) - Volume 3
P. 95

CPS1952 Michele N. et al.
            an arbitrary number of von Mises components can be used, we only use two
            because areas with seasonal malaria transmission typically have one or two
            main seasons (Stuckey et al. 2014).
                Based on the fitted R2vM curve, we identify the transmission periods by
            marking the months where the curve is at or above 1/12. In this way, we can
            also  obtain  the  start,  end  and  length  of  each  season.  If  there  is  only  one
            transmission period, we fit a rescaled, one component von Mises density to
            the monthly proportions and estimate the seasonality statistics based on this
            instead.
                To  obtain  the  uncertainty  associated  with  the  derived  statistics,  we
            summarise the results from 100 posterior samples of the monthly proportions.
            By  looking  at  the  proportion  of  times  a  location  is  deemed  bimodal  or
            unimodal,  we  can  obtain  the  majority  decision  as  well  as  the  degree  of
            certainty.  Based  on  this,  we  can  analyse  the  uncertainty  in  the  estimated
            seasonal characteristics. For the start, end and length of the transmission, we
            can obtain the means and standard deviations.

            2.4. Adjusted seasonality index
                    The seasonality index introduced in Section 2.1 does not work well for
            bimodal distributions since the entropy does not account for the two peaks
            and only considers the overall distribution in a year which typically appears as
            more even than a unimodal one. To better reflect the degree of seasonality,
            we adapt the entropy for bimodal distribution at location  using the fitted
            R2vM function as follows:

                                     ̃
                                      =   (1)  + (1  −  )  (1) ,
                                      

                                        12                    (,  ,  )
                          ℎ   ()  = ∑  (,  ,  )  (          )
                                                          2
                                                    
                                           
                                                 
                                       =1                        

            for =1,2 and the terms are as defined before. For consistency, we also base
            the adjusted seasonality index for unimodal distributions on the fitted one
            component von Mises density.

            3.   Results
                We illustrate our method using case data from the LAC region and restrict
            our analysis to Plasmodium vivax (Pv), the dominant malaria species there. We
            study the smallest administrative units available over each area and use their
            centroid coordinates as their point locations.
                For the years 2009-2016, we can compute monthly median case counts for
            1 ADMIN1 (state) unit and 567 ADMIN2 (municipalities) units in Brazil, 458

                                                                84 | I S I   W S C   2 0 1 9
   90   91   92   93   94   95   96   97   98   99   100