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CPS1108 Collins O. et al.

                            Evaluation and comparison of patterns of
                         maternal complications using generalised linear
                                 models of count data time series
                                                  1, 2
                                  Collins Odhiambo   , Freda Kinoti 2
                     1 Institute of Mathematical Sciences, Strathmore University, Nairobi, Kenya
             2 Department of Clinical Medicine and Therapeutics/CRISS Plus/School of Medicine, University
                                        of Nairobi, Nairobi, Kenya

            Abstract
            Studying patterns of maternal complications is critical before, during and after
            childbirth.  However,  there  is  limited  information  on  comparative  trends  of
            different maternal complications, particularly, in a resource-limited setting. In
            this study we fit six different types of maternal complications namely ante-
            partum  haemorrhage  (APH),  eclampsia,  obstructed  labour,  post-partum
            haemorrhage  (PPH),  ruptured  uterus  and  sepsis  to  time  series  generalized
            linear model. We systematically compare the performance of the model in
            light  of  real  data  by  checking  its  flexibility  and  serial  correlation  and  the
            conditional  distribution.  We  then,  compute  model  fitting,  assessment  and
            prediction analysis for each maternal complication. Additionally, we provide a
            comparative review of the results by assessing the effect of basic emergency
            obstetric  and  new-born  care  (BEmONC)  and  comprehensive  emergency
            obstetric  and  new-born  care  (CEmONC)  services  on  trends  in  maternal
            complications. Results show that women with APH, eclampsia and obstructed
            labour at the time of delivery are significantly high. Complication rates did not
            vary by maternal regions. Providers who perform obstetrical care should be
            alert  to  the  high  rate  of  maternal  medical  complications  associated  with
            obstructed labour. Introduction BEmONC  and CEmONC  package improved
            performance of providers in reducing maternal and newborn complications
            and mortality.

            Keywords
            Maternal  complications;  Count  Data  time  series;  Trends,  Goodness-of-fit;
            Conditional distribution

            1.  Introduction
                Maternal  complications  namely  ante-partum  haemorrhage  (APH),
            eclampsia,  obstructed  labour,  post-partum  haemorrhage  (PPH),  ruptured
            uterus and sepsis constitute to one of the leading causes of the burden of
            disease for women of reproductive age throughout the world and contribute
            to high levels of mortality and disability in developing regions 1. Maternal
            conditions dominate the burden of reproductive ill-health, accounting for at
            least 25% of the global burden of diseases, particularly in Kenya.


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