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CPS2204 T. von R. et al.
                       (, ) = (( , ), … , ( , )) = ( (), … ,  ()) .
                                                      
                                                                           
                                                 
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                Influence  analysis  in  nonlinear  regression  is  not  widely  explored.  We
            propose a new influence measure for assessing the influence of single and
            multiple observations on the parameter estimates in a nonlinear regression
            model using differentiation approach. The differentiation approach is used in
            linear  regression  to  construct  the  influence  measure  ̂ where  the  EIC
                                                                      ,
            stands for Empirical Influence Curve (see e.g. Belsley et al. (1980), Chatterjee
            and Hadi (1988) and Cook and Weisberg (1982)). Originally EIC measure was
            derived from the influence curve, a theoretical concept introduced by Hampel
            (1974).
                We extend the ideas of using the differentiation approach for measuring
            the  influence  of  an  observation  on  the  parameter  estimate  in  nonlinear
            regression models. Two new influence measures for the parameter estimates
            in the nonlinear regression model (1) will be derived: the  ̂  and  ̂ , .
                                                                                    
                                                                        ,
            The abbreviation stands for Differentiation approach & Influence Measure.
            The first diagnostic measure,  ̂ , is used to assess the influence of a single
                                             ,
            observation  on  all  parameter  estimates  in  the  model,  simultaneously.  It  is
            constructed  when  all  parameters  are  estimated  from  a  perturbed  model,
            presented in (2) later on, and it is referred to as the joint-parameter influence
            measure. The  ̂ , ., on the other hand, is used to assess the influence of a
                               
            single  observation  on  the  jth  parameter  estimate  in  the  model.  When
            constructing   ̂ , ., only the jth parameter is estimated from the perturbed
                               
            model, later defined in (2): the other parameters are estimated from an unper-

            b turbed model and regarded to be known. The  ̂    is referred to as the
                                                                ,,
            marginal-parameter influence measure. We will now start with the definition
            of  ̂ . Consider the following perturbed nonlinear model
                   ,
                                          = (, ) +  ,                     (2)
                                                         
                                          
                                 −1
                              2
            where  ~ (,   ( )),   is the weight such that 0 < ωk ≤ 1 and the
                                      
                                           
                    
                        
            weight matrix ( ) = (1, … . ,  , …,1).
                                                
                               
            Definition  2.1.  The  influence  measure  for  assessing  the  influence  of  the  kth
                          ̂
            observation on  is defined as the following derivative

                                                
                                      ̂ =    ( )| =1,           (3)
                                         ,
                                                      
                   ̂
            where ( )is  the  weighted  least  squares  estimate  of  in  the  perturbed
                       
            model (2).
                                                                     ̂
                                                            ̂
                Observe that, in Definition 2.1, if ωk → 1, then ( ) → , the unweighted
                                                                
            least squares estimate.
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