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CPS2003 Bruno de S. et al.
                      grey areas represent municipalities of non-significant effects for PTB
                               incidence rates (credible intervals containing zero)
                      Regarding  time,  Figure  5  shows  a  slightly  non-linear  decreasing  effect
                  between 2000 and 2010, confirming the capacity of the model to pick up the
                  decreasing effect of PTB new cases shown in the previous descriptive analysis
                  (Figure 1a).


























                   Figure 5: Estimated nonlinear effect of year in PTB incidence rates, together
                                          with 95% credible intervals.

                  4.   Conclusion
                      Nunes et al. [3] identified two main regions, MAL and MAP, as being high
                  risk areas for contracting PTB in Portugal in 2001. The results of our study also
                  suggest a clear urban problem, with MAL (Region II) and the MAP (Region I)
                  being  two  of  the  main  areas  identified  as  statistically  significant  areas  of
                  increased PTB incidence rates (Figure 4). Although with smaller numbers of
                  new cases of PTB, Algarve and Lower Alentejo (Region III) also emerge as a
                  region within this category.   The metropolitan areas of Lisbon (Region II) and
                  Oporto (Region I) correspond to two regions with high population density,
                  resulting immediately in an agglomeration of the main risk groups associated
                  with  high  incidence  of  tuberculosis  (e.g.  homeless,  unemployed,  IV  drug
                  addicts and other drugs). On the other hand, Region III which includes Algarve,
                  not corresponding to an area of high population density throughout the year,
                  it is associated with seasonal tourism and workers particularly through the
                  months of April to September, when it also becomes a high density populated
                  region. It is worth noticing that, after Lisbon with 52% of the total of foreigners
                  living in Portugal, Algarve, North and Center of Portugal, are the three regions
                  with the highest percentage of foreigners (13%, each).  In addition, 12% of


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