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CPS1934 Atikur R. K. et al.


                           Prediction of daily respiratory tract infection
                                 episodes from prescription data
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                                                   2
                                1
                  Atikur R. Khan , M. Towhidul Islam , Tabin Hasan , Saleheen Khan
                              1 Gulf University for Science and Technology, Kuwai
                               2 Independent University of Bangladesh, Dhaka
                            3 American International University - Bangladesh, Dhaka
                                     4 Minnesota State University, USA

            Abstract
            Changing weather pattern may directly or indirectly affect the incidence and
            severity  of  respiratory  tract  infections  causing  huge  economic  burden  for
            healthcare services. Early warning for severity and extent of this infection may
            help healthcare service providers to prepare for any epidemic well before in
            time. Our aim in this paper is to explore the relationship between respiratory
            tract infection episodes and climatic factors and to predict the number of daily
            episodes in different weather zones defined by the coverage areas of active
            weather stations in Bangladesh. Prescription data collected from clinics are
            integrated  with  climatic  factors  of  the  nearest  weather  stations,  and  this
            integrated  dataset  is  used  to  predict  the  daily  respiratory  tract  infection
            episodes in response to climatic factors. We apply panel generalized linear
            models and show that the number of episodes increases in a greater extent
            for increasing magnitude of rolling standard deviation of relative humidity and
            rolling mean of wind speed. A 7-day ahead forecast of number of episodes
            based on rolling window models of regression tree and random forest are
            produced to know the severity of epidemic for healthcare planning, and a
            further 1-day ahead confirmation forecast is produced to assess the necessity
            of healthcare service plan adopted based on a 7-day ahead forecast. Root
            mean squared forecast error computed both for 7-day ahead and 1-day ahead
            forecasts both from regression tree and random forest provide qualitatively
            similar results, except for three weather stations where unusually high number
            of episodes are observed because of climatic extremes and high level of air
            pollution.

            Keywords
            Panel generalized linear model; prescription data; respiratory tract infection;
            regression tree; random forest

            1.   Introduction
                Respiratory  tract  infections  (RTI)  are  the  most  common  infections
            worldwide causing a considerable economic burden to healthcare services.
            There  are  substantial  evidences  on  the  seasonal  variation  of  respiratory

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