Page 182 - Contributed Paper Session (CPS) - Volume 4
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CPS2169 Carmen D. Tekwe et al.
                  school-based  interventions  as  targeted  interventions  designed  to  reduce
                  sedentary behaviour among children. An example of such behavioural school-
                  based intervention is the activity permissive learning environment (Benden, et
                  al. 2014). Activity permissive learning environments introduce stand-biased
                  desks into classrooms as a means of increasing physical activity among school-
                  aged children. By reducing sedentary behaviour, physical activity behaviour is
                  encouraged  during  the  school  day,  and  devices  such  as  physical  activity
                  monitors are used to assess the behavioural patterns of physical activity. These
                  devices provide estimates of school day energy expenditure (SDEE), the total
                  amount  of  energy  or  calories  expended  by  the  body,  to  perform  physical
                  activity and routine bodily functions during the school day. Overweight and
                  obesity in children are defined based on age- and sex- adjusted body mass
                  indexes (BMI) in the upper percentile ranges. However, most studies assessing
                  impacts of interventions on BMI rely on traditional linear regression models
                  designed  to  assess  intervention  effects  on  children  within  ``normal''  BMI
                  percentile ranges, limiting assessments of how interventions affect children at
                  higher  risks  for  overweight  and  obesity.  Thus,  statistical  approaches  that
                  permit evaluations of covariates effects across the entire distribution of BMI
                  are  preferable  for  assessing  their  effects  on  subjects  at  higher  risks  for
                  developing overweight or obesity (Koenker, 1978). Quantile regression is a
                  statistical  technique  used  to  estimate  effects  of  predictors  on  quantile
                  functions of a response. Examples of quantile functions include the median,
                  the 85th and the 95th percentiles of the outcome. A drawback to the use of
                  classical mean regression models in modelling BMI as an outcome is that these
                  methods provide incomplete answers to questions related to BMI values that
                  lie within the tails of its distribution. Additionally, covariates such as SDEE and
                  age  may  influence  the  quantile  functions  differently.  Therefore,  statistical
                  approaches  that  allow  one  to  determine  covariate  effects  across  the  full
                  spectrum of quantile functions of BMI is preferable in obesity studies (Koenker,
                  1978).
                      Our  current  work  was  motivated  by  a  problem  in  childhood  obesity
                  research.  In  a  recent  study,  standbiased  desks  were  introduced  to  three
                  elementary schools in a Texas school district as a means of increasing physical
                  activity. A research question of interest was to determine the impact of SDEE
                  obtained at baseline on subsequent risks for obesity. The recruited children
                  were  given  BodyMedia  SenseWear®  armband  devices  (BodyMedia,
                  Pittsburgh,  PA)  to  measure  their  energy  expenditure  during  school  hours,
                  while sex- and age- adjusted BMI was used as an indicator for obesity. Physical
                  activity monitoring devices are designed to measure the intensity of physical
                  activity. Data from these devices are collected either at the second or minute
                  level over multiple days resulting in high dimensional longitudinal data that
                  appear as curves. Thus, SDEE data are collected over time and can easily be

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